CLOTRIMAZOLE@1 %@TOPICAL@SPRAY, NON-AEROSOL (ML)

A novel simple isocratic HPLC method with UV detection for the determination of three compounds in spray solution (active component clotrimazole and two degradation products imidazole and (2-chlorophenyl)diphenylmethanol) using ibuprofen as an internal standard was developed and validated. The complications with different acido-basic properties of the analysed compounds in HPLC separation – while clotrimazole has pKa 4.7, imidazole has pKa 6.9 compared to relatively more acidic (2-chlorophenyl)diphenylmethanol – were finally overcome using a 3.5 μm Zorbax® SB-Phenyl column (75 mm × 4.6 mm i.d., Agilent Technologies).

GEHWOL FUSSKRAFT NAIL AND SKIN PROTECTION- clotrimazole spray  Eduard Gerlach oHG

: Transdermal spray (TS) of clotrimazole (CTZ) was formulated to improve the drug transport through the skin up to 12 h to achieve the antifungal efficacy.

(clotrimazole) spray - DailyMed

Antifungal drops and spray for dogs and cats. Recommended for dermatological conditions responsive to Clotrimazole. : The aim of present study was to formulate and evaluate antifungal transdermal spray to improve the permeation of clotrimazole across the skin and to decrease the dosing frequency in fungal infection.

Formulation and evaluation of clotrimazole transdermal spray

: The aim of present study was to formulate and evaluate antifungal transdermal spray to improve the permeation of clotrimazole across the skin and to decrease the dosing frequency in fungal infection.

clotrimazole 1 % topical spray, No photos.


Several antifungal topical treatments are available without a doctor's prescription. They should be applied on clean, dry skin. Terbinafine is available as a cream, solution or spray formulation, while naftifine is available in cream and gel formulations. Tolnaftate is available in cream, spray and solution formulation, while clotrimazole is available in cream, spray and powder form. Miconazole has been shown to be effective for jock itch but has been marketed mostly for vaginal yeast infection in cream and vaginal suppository form. Topical antifungal treatment has few side effects, but the area may continue to be irritated for several days while healing occurs. If symptoms persist after a week or more of topical antifungal treatment, a physician should be consulted, as different or stronger medication may be required.Note: This page contains information about the side effects of clotrimazole topical. Some of the dosage forms included on this document may not apply to the brand name FungiCURE Pump Spray.Clotrimazole is a topical antifungal for dogs and cats that aids in the treatment of fungal infections and other skin disorders. It contains 1% clotrimazole that may be effective against Malassezia pachydermatitis and Microsporum canis. It is available in a 2 oz spray or 1 oz dropper bottle for convenient administration. Consult with your veterinarian before using this product, and follow their specific guidelines for use.: Transdermal spray (TS) of clotrimazole (CTZ) was formulated to improve the drug transport through the skin up to 12 h to achieve the antifungal efficacy.